Drug Design and Synthesis
- •Preparation of positive drugs and standard samples
- •Design and synthesis of F18-labeled, fluorescent-labeled, biotin-labeled probes
- •Design and synthesis of PROTACs
- •Synthesis of raw materials, intermediates, impurities, and metabolites
- •Synthesis of tritiated drugs
- •Synthesis and resolution of chiral drugs
- •Enzymatic synthesis of chiral intermediates for pharmaceuticals
- •High-quality synthesis ranging from milligram to hundred-kilogram levels…
Process Development of the Synthetic Route to these
- •Rimegepant (BMS-927711)
- •Zavegepant (AJ919)
- •Ubrogepant (MK-1602)
- •Gefapixant（AF-219, MK-7264）
- •Firsocostat (ND-630)
- •Hypoxystat
- •Zerencotrep (Pico145, HC-608)
- •D-Luciferin potassium salt
- •Others：84-B10, CPAG-1, W146, SP141, HC-070, M110。
